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This does not establish general repair of damaged human DNA

Priority areas include establishing standardized and quantitative methods for GSH/GSSG measurement and mapping redox heterogeneity across tumor types, as current assays lack spatial and temporal accuracy

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DA Wt branching and Plp1 expression were significantly increased upon addition of C75 (Fig

As with doxorubicin, cisplatin treatment also results in ROS generation, which is neutralised by the NADPH-powered glutathione system, warranting investigation of this strategy for other forms of chemotherapy which are detoxified via this system